Dr. Sukla Ghosh

Regeneration Biology



Department of Biophysics, Molecular Biology & Bioinformatics

University of Calcutta, Kolkata, India

Email: suklagh2010@gmail.com

B.Sc. (Honors) Visva- Bharati University, 1977

M.Sc. (Zoology) Visva- Bharati University, 1979

Ph.D (Biochemistry) Calcutta University, 1987

Research Statement

Among the vertebrates, urodele amphibians and fish have the remarkable ability to regenerate their lost body parts as adults and regain functional activity. A variety of body parts can be replaced like fin/limb, heart, lens, jaw and retina, of which CNS regeneration is most intriguing. Our aim is to study spinal cord regeneration in two different regeneration competent species, like axolotl (Ambystoma mexicanum) and zebrafish (Danio rerio). Present strategy is to use these excellent models to discover the signals that are responsible for initiation and maintenance of regeneration response in spinal cord after injury. The nature of these signals, their similarities and dissimilarities, will dictate the path to be chosen for inducing regeneration in higher vertebrates. We have characterized the cellular events underlying the regeneration process in zebrafish after inflicting spinal cord injury comparable to mammalian mode of injury. We are also taking a genomics approach to identify putative target genes responsible for controlling different events during regeneration by using cDNA array in zebrafish.



2015-present Professor Department of Biophysics, Molecular Biology & Bioinformatics, University of Calcutta, Kolkata, India
2005-2015 Associate Professor Department of Biophysics, Molecular Biology & Bioinformatics, University of Calcutta, Kolkata, India
2003 - 2005 Reader Department of Zoology, University of Delhi, Delhi, India
2000 - April 2003 Postgraduate Researcher Department of Cell and Developmental Biology, University of California, Irvine, CA.
Supervisor: Dr. David Gardiner and Dr. Susan V. Bryant
1999 - 2000 Senior Research Associate Biophysics Division, Saha Institute of Nuclear Physics, Calcutta, India.
1998-1999 Postdoctoral Research Associate Chittaranjan National Cancer Institute, Calcutta, India.
Supervisor: Dr. A. Chatterjee.
1995 -1997 Postdoctoral Research Associate Muscle Development Unit, Royal Veterinary College, London, U.K.
Supervisor: Dr. G. K. Dhoot
1992-1994 Postdoctoral Research Associate Developmental Biology Unit, Division of Cellular and Molecular Biology, Institute of Child Health, London, U.K.
Supervisor: Dr. P. Ferretti
1987-1990 Postdoctoral Research Associate Department of Biochemistry, Meharry Medical College, Nashville, TN.
Supervisor: Prof. Salil K. Das

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